Response Times Matter – Medical

Beating the Clock: When Time is Muscle

Johns Hopkins University

Summer 2009

“When time is muscle, every little bit counts. A few minutes here and there can add up to a great difference – in saving a life, and in saving a heart. The next step was to get those patients to treatment even faster. Instead of waiting for the on-call balloon team to arrive, Trost devised a plan to use people who are already there – a critical care unit nurse, radiation technologist, and an emergency physician – to serve as a transition team, while the regular interventional cardiology team is en route.”



Stroke 2006 Jan;37(1):263-6. Epub 2005 Dec 8.

Time is brain–quantified.

Conclusions— Quantitative estimates of the pace of neural circuitry loss in human ischemic stroke emphasize the time urgency of stroke care. The typical patient loses 1.9 million neurons each minute in which stroke is untreated.

Stroke. 2006 Jan;37(1):10.

The time man has cometh to brain: tick…death….tick…death.





Journal of the American College of Cardiology

Volume 52, Issue 15, October 2008 DOI: 10.1016/j.jacc.2008.07.011

 PDF Article

Time Is Muscle: Translation Into Practice

Elliott M. Antman


“By focusing now on system efforts for improvements in timely care for STEMI, we will complete the cycle of research initiated by Reimer and Jennings (6) 30 years ago. Time is muscle … we must translate that into practice.”

Time Is Muscle

June 7, 2016 Cooper University Healthcare

“The phrase that is often used by cardiologists is “Time Is Muscle,” meaning the longer you wait to get someone in for treatment the more damage that can occur to the heart muscle and the less likely are the chances for recovery. However, this requires a well-coordinated team of EMS, emergency room physicians, support staff, Cath Lab technicians, and nurses.”



Time is muscle in primary PCI: the strength of the evidence grows

by C. Michael Gibsona,*, James A. de Lemosb , Elliott M. Antmana

Brigham and Women’s Hospital and the Department of Medicine,

Harvard Medical School, USA b Cardiovascular Division UT Southwestern Medical School


This editorial refers to “Time-to-treatment significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute myocardial infarction treated by primary angioplasty” by G. De Luca et al. on page 1009–iW1saklinbHeGVp3


“These data add to a growing body of literature suggesting that renewed efforts are needed to reduce symptom-to-door and door to-balloon times in order to improve myocardial perfusion, myocardial salvage and clinical outcomes among patients undergoing primary PCI for STEMI.1”

“The other potential target for improvement lies in shortening symptom-to-door times.”

“The present study lends further support to an intuitive and straightforward paradigm: prompt re-perfusion, whether achieved pharmacologically or through PCI, is associated with improved angiographic, electrocardiographic and clinical outcomes. We have witnessed a relentless push in the “new device” era to open arteries “better”, but now is the time to emphasize the need to open them “quicker” in the setting of primary PCI. Now is the time to face the new challenge of educating both patients and providers to implement strategies to minimize delays in primary PCI.”



Time is Brain – Think FAST When Stroke Happens

Stroke Alliance For Europe – Posted by admin on Mar 17, 2017

Stroke is a serious, like-threatening medical condition that occurs when the blood supply to part of the brain is cut off. It is a medical emergency because time plays a vital role in the life of the person having a stroke. Minutes can make a difference between life and death, the difference between brain cells that are saved and brain cells that are damaged forever, between recovery and lifelong disability. Every minute the brain is oxygen deprived, brain cells get irreversibly damaged, so the longer door to needle time, the bigger the injury to the brain.



Call 9-1-1. First and Fast Preserves Heart Muscle


“When a heart attack strikes, swift action can save a life. Physicians like to say “Time is muscle” – meaning- the faster you call and the faster you get treatment- the better your chances of preserving heart function.”




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